Ingredients: Valerian Extract
Dosage: 60 Veg. Capsules/ 30 Day Supply
Indfrag is one of the leading manufacturers of dietary supplements. Indfrag supplies high quality products to Fortune 500 pharmaceutical and cosmetics companies, as well as the world's most well known dietary supplement brands.
Our commitment to our customers is guaranteed with our in-house manufacturing process. Indfrag controls and carefully monitors every step of the production process, from the supplement formulation to the careful selection and extraction of raw materials to preserve potency. This process also ensures that you will be buying the freshest supplements possible, as your purchase will be shipped directly to you from the manufacturing plant.
All capsules are vegetarian with no animal products used. All Indfrag supplements are GMO free and only heat sterilized, not irradiated.
Quality Certifications and Systems: ISO 9001 Quality System audited by a company in European Union. Kosher. CGMP (Current Good Manufacturing Practices).
Valerian is a plant native to Europe and Northern Asia. It has been used to cure insomnia, anxiety and nervous conditions since the days of the ancient Greeks and Romans.
Valerian root contains many active ingredients that have been found to contribute to the herb's sedative properties. Sleep is regulated in the human body by neurotransmitters in the central nervous system known as GABA-A receptors. Clinical trials have show that valerian extracts interact with the GABA-A receptors and cause a sedative effect. This may also be the cause of the calming effect of valerian.
Valerian appears to have therapeutic value as a tranquilizer and sleep aid for people suffering from mild to moderately severe insomnia. Clinical studies show that test subjects taking valerian extract fell asleep faster and experienced more restful sleep.
Safety reports show that valerian is not habit forming when used as directed. The German Commission E (a governmental regulatory agency) has declared valerian safe for treating "restlessness and sleeping disorders brought on by nervous conditions".
References
- Attele AS, Xie JT, Yuan CS. Treatment of insomnia: an alternative approach. Altern Med Rev 2000; 5: 249-59.[Medline]
- Balderer G, Borbely AA. Effect of valerian on human sleep. Psychopharmacology (Berl). 1985;87(4):406-Donath F, Quispe S, Diefenbach K, Maurer A, Fietze I, Roots I. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality. Pharmacopsychiatry. 2000 Mar;33(2):47-53
- Houghton PJ. The biological activity of Valerian and related plants. J Ethnopharmacol. 1988 Feb-Mar;22(2):121-42
- Houghton PJ. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol. 1999 May;51(5):505-12
- 19. Last G. On the treatment of insomnia. Hippokrates. 1969 Jan 15;40(1):28-33
- Leathwood PD, Chauffard F, Heck E, Munoz-Box R. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav. 1982 Jul;17(1):65-71
- Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med. 1985 Apr;(2):144-8
- Leuschner J, Muller J, Rudmann M. Characterization of the central nervous depressant activity of a commercially available valerian root extract. Arzneimittelforschung 1993; 43: 638-41
- Molodozhnikova LM. Medicinal valerian. Feldsher Akush. 1988 Jan;53(1):44-6
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